Lenalidomide Brands in India

Description

What is Lenalidomide?

Lenalidomide is an anti-cancer medication. The medicine checks the cancer growth, blocks new blood vessel growth in tumors, and helps the immune system fight cancer.

Lenalidomide is FDA approved Internationally. However, several pharmacies of high repute in India manufacture the medicine under their specific brands, Natco pharma Lenalid (Lenalidomide) is one of them.

The medication Lenalidomide is used to treat certain types of cancers by helping the immune system fight the disease and slowing down the growth of cancer cells.

The medicine is prescribed particularly for –

– Multiple myeloma (a type of bone marrow cancer) after a hematopoietic stem-cell transplant (HSCT; a procedure in which certain blood cells are removed from the body and then returned to the body).

– Mantle cell lymphoma (a fast-growing cancer that begins in the cells of the immune system) patients who have been treated with bortezomib and at least one other medication.

– Myelodysplastic syndrome (MDS) disorders resulting from poorly formed or dysfunctional blood cells that might cause anemia.

It might also be a part of clinical trials for other cancer types.

What are the Lenalidomide side effects?

Most of the medication’s side effects don’t need any medical assistance. As soon as your body adjusts to the medication, these are gone. If any persist, consult your doctor.

Some common side effects of Lenalidomide are –

• Itching
• Breathlessness
• Dizziness
• Decreased white blood cell count (neutrophils)
• Rashes
• Joint pain
• Diarrhea
• Low blood platelets
• Peripheral edema
• Upper respiratory tract infection
• Decreased appetite
• Nasopharyngitis (throat and nasal passages’ inflammation)

Lenalidomide Generic in India

As mentioned above, Lenalidomide is used in the treatment of various cancer types.

This medicine is available as capsules that are taken once a daily.

In India, its generic versions are available at affordable rates by various pharmaceutical brands, primarily –

• Dr Reddy’s
• Natco Pharma
• Cipla
• Glenmark
• Zydus

Indian Manufacturer	Brand Name	Prices (a bottle of 30 capsules)
Dr Reddy’s	Lenangio	₹2196 to ₹9296 6 variant(s)
Natco Pharma	Lenalid	₹2196 to ₹9296 5 variants
Cipla	Lenmid	₹400 to ₹3076 4 variants

The medicine is available in different strengths, some of which are mentioned below –

Lenalidomide 5 mg in India

It belongs to a group of medicines that affect how your immune system works. The medication is used in the treatment of multiple myeloma and myelodysplastic syndrome.

Lenalidomide 10 mg in India (once a day orally)

Lenalidomide 25 mg in India (once a day orally)

For the treatment of certain types of MDS. The medicine targets especially those disease cells that are associated with a specific part of the chromosomes in the blood cells.

Lenalidomide medicine cost

Global Price

The price of lenalidomide can be quite high globally, specially in the United States the prices are high for this medicine. However, the Indian generic version of Lenalidomide cost is very less.

In the UK, the cost of Lenalidomide is also high.

Lenalidomide Price in India

The cost of Lenalidomide in India can vary significantly depending on the dosage and brand. For example, Natco Lenalid 5 mg and 10 mg capsules typically cost around ₹4,000 to ₹8,000 for a bottle of 30 capsules.

Higher dosages like 25 mg can cost between ₹16,000 and ₹20,000 for the same quantity.

Prices can differ slightly between different pharmacies and medicine strength.

Given the considerable difference in pricing between India and other countries, compare costs and consult with your doctor for the most cost-effective options.

Where to Buy Lenalidomide Online in India?

Buying Lenalidomide online in India is a breeze. You can choose from various online portals of reputed pharmacies.

Get a Prescription: Consult your doctor for a prescription.

Choose a trusted supplier: Use reputable supplier.

You can also contact Delightaid Health, we can help you to get high quality medicine Lenalidomide at the lowest discounted cost. Please contact us via Email, WhatsApp or simply filling query form in our website bottom section or contact us page.

The customer will have to present a medical prescription (legal) prescribed from a doctor.

How to take Lenalidomide?

Lenalidomide is usually taken orally. Its dose and duration are as advised by your doctor. Here, take a look at how to take Lenalidomide:

• Lenalid 10 Capsule may be taken with or without food, but it is better to take it at a fixed time.
• The capsule should be swallowed whole with water. Do not break, chew, or open the capsules.
• The dosage may differ based on the specific condition, such as myelodysplastic syndromes or mantle cell lymphoma. The doctor will adjust the dose based on the patient’s response and any side effects.

Please note: Follow the doctor’s instructions carefully. Never adjust the dosage or discontinue use without consulting your doctor.

What is the Lenalidomide mechanism of action in Multiple Myeloma?

Lenalidomide works by –

• Killing cancer cells in the bone marrow and helps it to produce normal blood cells
• Preventing new blood vessel formation, starving the tumor cells of nutrients and oxygen, and limiting their growth

Overall, lenalidomide’s ability to target multiple pathways makes it a highly effective therapy in treating multiple myeloma, particularly when used in combination with other agents like dexamethasone or proteasome inhibitors.

Lenalidomide vs Pomalidomide and Thalidomide

Lenalidomide, Pomalidomide, and Thalidomide are oral immunomodulatory drugs for multiple myeloma treatment. While they share similarities, there are key differences as well:

	Lenalidomide	Pomalidomide	Thalidomide
Usage	Widely used for multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma. It is often used in combination with other drugs for greater efficacy.	Reserved for multiple myeloma patients who have not responded well to at least two therapies before, including lenalidomide and a proteasome inhibitor.	In the treatment of various cancers, particularly multiple myeloma
Chemical Structure and Mechanism	A derivative of thalidomide, it modulates the immune system to target and destroy cancer cells. It also inhibits angiogenesis (the formation of new blood vessels that tumors need to grow).	A newer derivative in the same class, designed to be more potent. It has a similar mechanism of action but with enhanced effects on the immune system, making it effective even in cases where lenalidomide or thalidomide has failed.	Is the parent compound and works by modulating the immune system, inhibiting angiogenesis (the formation of new blood vessels), and directly affecting tumor cells.
Side Effects	Both drugs share common side effects such as fatigue, low blood counts, and an increased risk of blood clots. However, pomalidomide may have a slightly higher incidence of severe side effects due to its potency.	same as Lenalidomide	Risk of severe birth defects if taken during pregnancy and can cause peripheral neuropathy (nerve damage), constipation, drowsiness, and an increased risk of blood clots.
Efficacy		Generally considered more potent and effective in relapsed or refractory multiple myeloma cases, especially after lenalidomide treatment has failed. However, its use is typically limited to more advanced stages due to its increased toxicity and cost.	Among the first IMiDs used to treat multiple myeloma and is effective, especially when combined with other therapies. However, its use is often limited by its side effects.
Cost	Expensive	More expensive than lenalidomide	Generally less expensive

Overall, while lenalidomide is often the first line of treatment in certain cancers, pomalidomide offers a critical option for patients whose disease has progressed despite other treatments​.

Thalidomide laid the groundwork for immunomodulatory cancer therapy, lenalidomide has largely superseded it due to its improved efficacy and reduced side effects. However, thalidomide still has a role in treatment, especially in specific clinical scenarios or regions with limited access to newer drugs​.

In Conclusion

Patients taking lenalidomide are closely monitored due to potential side effects, which can include low blood cell counts, blood clots, fatigue, and an increased risk of secondary cancers. Despite these risks, lenalidomide has proven to be an effective therapy in extending survival and improving the quality of life for many patients with these challenging cancers.

FAQs

Is Indian generic lenalidomide as good as Inventor lenalidomide?

Yes, the Indian generic lenalidomide is found to be as effective as the inventor lenalidomide for treatment. It yields similar improved response and survival outcomes without extra toxic effects.

Is lenalidomide a chemotherapy drug?

No, lenalidomide isn’t a chemotherapy medication. It’s an anti-cancer medication that helps your immune system fight cancer more effectively.

When should you take lenalidomide?

Take lenalidomide every day at the same time. 

How much does lenalidomide cost?

The cost of lenalidomide varies as per the medicine’s strength, dosage, and pharmacy chosen. 

How does lenalidomide work?

Lenalidomide works by fighting cancer cells, stopping cancer cell growth, and blocking the blood supply to tumor cells. 

How long can you take lenalidomide?

It is usually taken for 21 days followed by a 7-day break. Also, the duration of lenalidomide treatment depends on the patient’s condition and the doctor’s advice.

How does lenalidomide work in multiple myeloma?

Lenalidomide kills cancer cells in the bone marrow, produces healthy blood cells, & limits the tumor growth. 

How long can you stay on lenalidomide?

You stay on lenalidomide as long as your doctor prescribes it and your health condition. 

Why is lenalidomide so expensive?

Lenalidomide is expensive because the company that invented it, invested immensely in research, clinical trials, and hiring the best talents. However, India has its affordable versions that are equally high in quality and efficacy. 

 

Disclaimer: The content on this website is derived from published literature and is intended for informational purposes only. All trademarks are the property of their respective owners.  We strives to provide accurate and reliable information, but does not guarantee or assume legal liability for its accuracy or completeness. The product prescribing information adheres to Indian drug approval standards and may not reflect regulatory approvals in other countries. This information is not a substitute for the professional advice and services of a qualified healthcare provider. All medical management advice should be based on the physician’s knowledge and expertise.

Consult a healthcare provider or pharmacist for the most accurate and up-to-date information.

 

References –

https://www.medindia.net/drugs/trade-names/lenalidomide.htm

https://en.wikipedia.org/wiki/Lenalidomide 

https://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(22)01752-9/fulltext 

https://www.cancerresearchuk.org/about-cancer/treatment/drugs/lenalidomide 

https://medlineplus.gov/druginfo/meds/a608001.html  

https://www.drugs.com/lenalidomide.html

 

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